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Pharmaceutics
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DEVELOPMENT AND EVALUATION OF ORAL CHEWABLE TABLETS AND ORODISINTEGRATING TABLETS OF TULSI LEAF POWDER FOR DIABETIC PATIENTS


Abstract

Author(s): Harshal A. Pawar, Keval J. Nandu, Khilan H. Khimasia

The objective of the present research work was to develop and optimize the chewable as well as Orodisintegrating tablet
formulation of Tulsi leaf powder. The phytochemical evaluation of Tulsi powder showed the presence of carbohydrates, alkaloids,
flavonoids, terpenoids, saponins, glycosides, steroids, and tannins. Tablets of Tulsi powder were prepared by direct compression
method. The prepared tablet formulations were evaluated for various post compression parameters. The results obtained for post
compression evaluation were within acceptable range. Among all the four formulations, F-1, F-2 and F-3 can be used as chewable
tablet since its disintegration time was more, whereas formulation F-4 can be used as orodisintegrating tablet since its
disintegration time in water as well as pH 6.8 phosphate buffer was found less than 30 seconds. The chewable and
Orodisintegrating tablet formulation of Tulsi leaf powder was successfully developed for diabetic patient. The developed herbal
formulations will provide better bioavailability and patient compliance as compared to conventional tablets. The developed
formulations presented as alternative to marketed throat lozenges to be used in common conditions of cough and sore throat with
wide acceptability among diabetics.

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Citations : 166

International Journal of Chemical and Pharmaceutical Analysis received 166 citations as per google scholar report

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