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Author(s): Dasharath Chavhan and Shrikant Patil

New oxazole derivative of substitutednaphthol were ecofriendly and efficiently be synthesized like 2-(2-amino-1, 3-oxazol-4-yl)-4- substitutednaphthalen-1-ol (5) by cyclization of 1-[2-(4-Substituted-1-hydroxynaphthalen-2-yl)-2-oxoethyl]thiocarbamide (4) by utilizing elemental sulphur as a chief, easily available, non toxic catalyst. All the reactions were carried out in ecofreindly solvent medium PEG 400 in a short period of time. The synthesized compounds were characterized by IR, NMR, Mass spectral and C, H, N elemental analysis.

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Citations : 440

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