Author(s): Neetu Arya and Neera Sahai
Mosquitoes are the vectors of various diseases. The extensive uses of synthetic organic insecticides during the last five decade have resulted in environmental pollution and also in the development of physiological resistance in major vector species. The present problem was proposed to be undertaken to provide suitable alternatives to control vector mosquito using biological control methods. Ageratum conyzoides whole plant of family Asteraceae was collected locally from Vidisha district of M.P. The crude extract were isolted and purified using colum chromatography, TLC, acid hydrolysis, methylation and other chemical methods. Alkaloid isolated from Ageratum conyzoides have shown larvicidal activity against Anopheles stephensi at concentration of 100 to 500 ppm. The LC50 value for second and fourth instar larvae were 181.97 and 165.96 ppm respectively. The results were quite dose dependents. The results obtained suggest that bioactive compound of Ageratum conyzoides could be used in search for new larvicidal compound of plant origin.