Author(s): Archana Singh, Suman Malik and Amar Sohail Mirza
Schiff bases are versatile ligands and play important role in medicinal and bioinorganic fields because of their wide spectrum of biological activities. Schiff bases are multipurpose ligands which are amalgamated from the condensation of carbonyl compounds with an amino compound. Schiff bases and their metal complexes are also used for industrial purposes and their metal complexes have been screened for their in vitro biological activities against bacteria, fungi and yeast. These complexes also show significant growth inhibitory activity against the bacteria like Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Klebsilla Pneumonia, etc. than the free ligands. Most of them show biological activities such as antibacterial, antifungal antioxidant, biocidal, antiviral as well as antitumor activity. It has been observed that the antimicrobial activities of these metal complexes are higher than that of the free ligand.