Author(s): Vishwas T S*, Gurupadayya B M, Maruthi R, Rupsheejain
The current work defines simple, precise, and economical method established on UV spectrophotometric technique for the simultaneous estimation of Atorvastatin (ATR) and Clopidogrel (CP) in capsule dosage form. The solvent used was methanol and the absorption maxima(λmax) for Atorvastatin & Clopidogrel was found to be 246nm &202nm respectively. The calibration curve of was linear over the range of 5-25μg/ml for both Atorvastatin and Clopidogrel. The method was then validated for different parameters like accuracy, precision, and linearity as per ICH guidelines. The method showed good reproducibility and recovery with % RSD in the favorable range. This method can be effectively employed for the day to day analysis of both drugs in the capsule dosage form.