Author(s): A.Glory Punitha and J. Prema Kumari
The present study deals with the synthesis of silver nanoparticles (AgNPs) using α- cyclodextrin (α- CD) as the reducing agent as well as capping agent and describe cost effective, novel and environment friendly synthesis of silver nanoparticles. This involves the synthesiszed nanoparticles by capping with different concentrations of α-cyclodextrin. The synthesiszed nanoparticles were characterized using Ultraviolet Visible Spectroscopy (UV-VIS), Fourier Transform Infra-Red (FT–IR) Spectroscopy, X-ray Diffraction studies (XRD) and Scanning Electron Microscope ( SEM). UV-Vis Spectroscopy, FT-IR Spectroscopy and X-ray diffraction study confirmed the formation of nanoparticles. SEM studies reveal the existence of spherical shaped particles of nano dimension. α- CD capped AgNPs coated with Imatinib an anticancer drug achieves a strong effect than Imatinib. This reduces the dosing frequency and side effect. Capping with α-cyclodextrin showed much pronounced enhancement in antibacterial behaviour in silver nanoparticles.