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Pharmaceutics
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SYNTHESIS OF POLYMERS BY MICROWAVE IRRADIATION AND CHARACTERIZATION FOR TASTE MASKING


Abstract

Author(s): Mohd. Shoeb, Nidhi. P. Sapkal

Polymers have been used as a main tool to control the drug release rate from the formulations and for its taste masking ability. Polymers were synthesized using 4-vinyl pyridine (4-VP), 2-hydroxy ethyl methacrylate (HEMA), methacrylic acid (MA), and methyl methacrylate (MMA) using free radical chain growth polymerization in microwave synthesis system. Characterization of polymers was done on various parameters of viscosity, solubility, molecular weight etc. The result revealed that the synthesized polymers are able to mask the taste of some bitter drugs like Cefuroxime axetil (CA), Cefpodoxime proxetil (CP) and Cefixime.

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